About Me

I am a junior at Duke studying Biomedical Engineering. My interdisciplinary expertise spans wet lab research, computational biology, and AI/ML applications in life sciences. From engineering iPSC-derived cells to fine-tuning protein language models, I bridge the gap between biological discovery and technological innovation to tackle complex biomedical challenges.

Experience

Skill

Education

Side Project

  • Programming & ML
    Python (Pandas, PyTorch, PyLabRobot), CAD, HTML, Machine Learning
  • Protein Language Models
    ESM2 fine-tuning, LoRA/PEFT techniques, constraint learning
  • Data Science & Analysis
    scRNA-seq analysis, time series forecasting (Prophet), feature engineering
  • Computational Biology
    ImageJ, Cell Profiler, automation pipelines, Nanopore sequencing
  • Wet Lab Techniques
    iPSC culturing, bacterial transformations, Cell Painting Assay, molecular biology
  • 2023 - 2027
    DUKE UNIVERSITY
    • Selected Courses
      • Linear Algebra & Application, Data Structures & Algorithms, Microelectronic Devices and Circuits, Quantitative Physiology and Biostatistical Applications, Deep Neural Networks, PDE & ODE
    • Leadership & Extracurriculars
      • Duke Chinese Student Association, Co-President
  • 2019 - 2023
    WESTERN RESERVE ACADEMY
    • Diploma Honors in Social Science, Science, Modern & Classical Languages, and Mathematics
  • TryIt
    A virtual try on app that allows a prompt-based, gamified, modular, and social virtual try on experience to explore endless personal fashion possibilities.
  • CalendarOCR
    An app that translates poster events from phone camera to calendar event and can be saved on device calendar. Ideal for college events.
  • Period Tracking Website
    A period tracking website for better health tracking.

Selected Experiences

Tetsuwan Scientific

Helped building AI-scientist to automate life science research in an 8-person startup team. I automated the bacterial trasnformation protocol, Nanopore sequencing pipeline, and colony picking through integrating 3D printed custom tools with liquid handler robots and developing computer vision approaches. I also contributed to the first lab automation community wikipedia page.

Lab Auto Wiki

Chory Lab

Applying robotics-aided directed evolution to study and engineer chromatin binding proteins. I worked on bacterial transformations, contributed to PyLabRobot (PLR), and automated plenty assays on robot, advancing the field of automated protein engineering and synthetic biology.

Barrett Lab

I worked at the Barrett lab throughout the summer at Broad and Harvard through the Harvard Stem Cell Institute Internship. I utilized iPSC-derived neural progenitor cells to study Down Syndrome-specific morphology, conducted Cell Painting Assay, and applied machine learning to extract key traits related to DS, reaching 83% prediction accuracy.

HSURV Abstract Book pg. 44

Navid Lab

I formulated a primal-dual constraint learning problem to tackle protein pathogenicity prediction. To achieve the desired outcome, I fine-tuned ESM2 models with PEFT LoRA and constraint relaxation to improve results by 5%. We are currently preparing the manuscript for submission.

Musah Lab

My lab implements an innovative way to engineer functional podocyte cells using human iPSCs. Using them as models to study Chronic Kidney Disease (CKD), I identified 6 important genetic pathways related to podocyte injury from scRNA-seq data that may serve as treatment targets for CKD.

Apple

Working with the data team at Apple Greater China, I constructed a Prophet-based ML model to predict 15-week Mac sales, improving MAPE by 56%. I performed feature engineering with Pandas and tested Lightgbm model to predict weekly iPhone sales. Successfully incorporated the final Prophet model into the data team's prediction workflow.

My Hobbies

Sports

I am a big fan of all sports. Check out some of my sports videos here!

Piano & Art

Creativity takes courage. Check out some of my paintings in this archive I built for my high school!

Traveling

Life is a daring adventure. Check out my latest travel video in Xinjiang!

Contact Me

bj142@duke.edu

330-734-7051

Download CV

Copyright Bowen Jiang